Systemic lupus erythematosus. ****************************** (SLE) is an autoimmune disease. In this disease, the immune system of the body mistakenly attacks healthy tissue. It can affect the skin, joints, kidneys, brain, and other organs. The four different types of lupus. ******************************** Systemic lupus erythematosus. Systemic lupus is the most common form of lupus—it's what most people mean when they refer to “lupus.” Systemic lupus can be mild or severe. Cutaneous lupus erythematosus. ... Drug-induced lupus erythematosus. ... Neonatal lupus. What causes SLE? ***************** The exact cause of SLE isn't known, but several factors have been associated with the disease. ... Causes of SLE ultraviolet rays. certain medications. viruses. physical or emotional stress. trauma. Recognizing potential symptoms of SLE. *************************************** severe fatigue. joint pain. joint swelling. headaches. a rash on the cheeks and nose, which is called a “butterfly rash” hair loss. anemia. blood-clotting problems. Treatment for SLE. ***************** anti-inflammatory medications for joint pain and stiffness, such as these options available online. steroid creams for rashes. corticosteroids to minimize the immune response. antimalarial drugs for skin and joint problems. disease modifying drugs or targeted immune system agents for more severe cases. SLE lupus diet. ************* diet that includes plenty of fruits, vegetables, and whole grains. It should also include moderate amounts of meats, poultry, and oily fish. If you have lupus, following a varied, healthy diet may help: Reduce inflammation and other symptoms. SLE lupus test. ************** There is no single diagnostic test for systemic lupus. The test you will hear most about is called the antinuclear antibody (ANA) test. This is not a specific test for lupus, however. In fact, a variety of laboratory tests are used to detect physical changes or conditions in your body that can occur with lupus.